Summary: Vibrio cholerae RfbT protein
Vibrio cholerae RfbT protein Provide feedback
This family consists of several RfbT proteins from Vibrio cholerae. It has been found that genetic alteration of the rfbT gene is responsible for serotype conversion of Vibrio cholerae O1  and determines the difference between the Ogawa and Inaba serotypes, in that the presence of rfbT is sufficient for Inaba-to-Ogawa serotype conversion .
Ito T, Hiramatsu K, Ohshita Y, Yokota T; , Microbiol Immunol 1993;37:281-288.: Mutations in the rfbT gene are responsible for the Ogawa to inaba serotype conversion in Vibrio cholerae O1. PUBMED:7688846 EPMC:7688846
Chiang SL, Mekalanos JJ; , Infect Immun 2000;68:6391-6397.: Construction of a Vibrio cholerae vaccine candidate using transposon delivery and FLP recombinase-mediated excision. PUBMED:11035750 EPMC:11035750
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR008890This family consists of several RfbT proteins from Vibrio cholerae. It has been found that genetic alteration of the rfbT gene is responsible for serotype conversion of V. cholerae O1 [PUBMED:7688846] and determines the difference between the Ogawa and Inaba serotypes, in that the presence of rfbT is sufficient for Inaba-to-Ogawa serotype conversion [PUBMED:11035750].
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Curation and family details
|Seed source:||Pfam-B_8029 (release 8.0)|
|Number in seed:||2|
|Number in full:||55|
|Average length of the domain:||238.30 aa|
|Average identity of full alignment:||95 %|
|Average coverage of the sequence by the domain:||99.24 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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