Summary: VirC1 protein
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This family consists of several bacterial VirC1 proteins. In Agrobacterium tumefaciens, a cis-active 24-base-pair sequence adjacent to the right border of the T-DNA, called overdrive, stimulates tumour formation by increasing the level of T-DNA processing. It is thought that the virC operon which enhances T-DNA processing probably does so because the VirC1 protein interacts with overdrive. It has now been shown that the virC1 gene product binds to overdrive but not to the right border of T-DNA .
Toro N, Datta A, Carmi OA, Young C, Prusti RK, Nester EW; , J Bacteriol 1989;171:6845-6849.: The Agrobacterium tumefaciens virC1 gene product binds to overdrive, a T-DNA transfer enhancer. PUBMED:2592351 EPMC:2592351
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This tab holds annotation information from the InterPro database.
InterPro entry IPR009744
This family consists of several bacterial VirC1 proteins. In Agrobacterium tumefaciens, a cis-active 24-base-pair sequence adjacent to the right border of the T-DNA, called overdrive, stimulates tumour formation by increasing the level of T-DNA processing. It is thought that the virC operon, which enhances T-DNA processing probably, does so because the VirC1 protein interacts with overdrive. It has now been shown that the virC1 gene product binds to overdrive but not to the right border of T-DNA [PUBMED:2592351].
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Curation and family details
|Seed source:||Pfam-B_11309 (release 10.0)|
|Number in seed:||4|
|Number in full:||74|
|Average length of the domain:||212.80 aa|
|Average identity of full alignment:||28 %|
|Average coverage of the sequence by the domain:||93.83 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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