Summary
This is the summary of UniProt entry TRXR1_RAT (O89049).
| Description: | Thioredoxin reductase 1, cytoplasmic EC=1.8.1.9 |
| Source organism: |
Rattus norvegicus (Rat)
(NCBI taxonomy ID
10116)
View Pfam proteome data. |
| Length: | 499 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | Pyr_redox_2 | 14 | 340 |
| low_complexity | n/a | 19 | 37 |
| Pfam A | Pyr_redox | 192 | 276 |
| disorder | n/a | 267 | 268 |
| disorder | n/a | 270 | 274 |
| disorder | n/a | 313 | 314 |
| Pfam A | Pyr_redox_dim | 370 | 483 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O89049. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MNDSKDAPKS YDFDLIIIGG GSGGLAAAKE AAKFDKKVMV LDFVTPTPLG
50 51
TRWGLGGTCV NVGCIPKKLM HQAALLGQAL KDSRNYGWKL EDTVKHDWEK
100 101
MTESVQNHIG SLNWGYRVAL REKKVVYENA YGKFIGPHKI MATNNKGKEK
150 151
VYSAERFLIA TGERPRYLGI PGDKEYCISS DDLFSLPYCP GKTLVVGASY
200 201
VALECAGFLA GIGLDVTVMV RSILLRGFDQ DMANKIGEHM EEHGIKFIRQ
250 251
FVPTKIEQIE AGTPGRLKVT AKSTNSEETI EDEFNTVLLA VGRDSCTRTI
300 301
GLETVGVKIN EKTGKIPVTD EEQTNVPYIY AIGDILEGKL ELTPVAIQAG
350 351
RLLAQRLYGG STVKCDYDNV PTTVFTPLEY GCCGLSEEKA VEKFGEENIE
400 401
VYHSFFWPLE WTVPSRDNNK CYAKVICNLK DNERVVGFHV LGPNAGEVTQ
450 451
GFAAALKCGL TKQQLDSTIG IHPVCAEIFT TLSVTKRSGG DILQSGCUG
499
Show the unformatted sequence. |
| Checksums: |
CRC64:B23E5B5E661B174E
MD5:8e403b6d97aa5617056610d582a6ea60
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
