Summary
This is the summary of UniProt entry RECQ5_HUMAN (O94762).
| Description: | ATP-dependent DNA helicase Q5 EC=3.6.4.12 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 991 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | DEAD | 31 | 203 |
| Pfam A | Helicase_C | 277 | 354 |
| low_complexity | n/a | 441 | 454 |
| disorder | n/a | 482 | 496 |
| low_complexity | n/a | 482 | 498 |
| disorder | n/a | 498 | 500 |
| disorder | n/a | 518 | 530 |
| disorder | n/a | 532 | 541 |
| disorder | n/a | 558 | 582 |
| disorder | n/a | 608 | 654 |
| Pfam A | RecQ5 | 625 | 829 |
| disorder | n/a | 659 | 760 |
| low_complexity | n/a | 730 | 749 |
| disorder | n/a | 763 | 776 |
| disorder | n/a | 778 | 910 |
| Pfam B | Pfam-B_2811 | 830 | 927 |
| disorder | n/a | 949 | 963 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O94762. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MSSHHTTFPF DPERRVRSTL KKVFGFDSFK TPLQESATMA VVKGNKDVFV
50 51
CMPTGAGKSL CYQLPALLAK GITIVVSPLI ALIQDQVDHL LTLKVRVSSL
100 101
NSKLSAQERK ELLADLEREK PQTKILYITP EMAASSSFQP TLNSLVSRHL
150 151
LSYLVVDEAH CVSQWGHDFR PDYLRLGALR SRLGHAPCVA LTATATPQVQ
200 201
EDVFAALHLK KPVAIFKTPC FRANLFYDVQ FKELISDPYG NLKDFCLKAL
250 251
GQEADKGLSG CGIVYCRTRE ACEQLAIELS CRGVNAKAYH AGLKASERTL
300 301
VQNDWMEEKV PVIVATISFG MGVDKANVRF VAHWNIAKSM AGYYQESGRA
350 351
GRDGKPSWCR LYYSRNDRDQ VSFLIRKEVA KLQEKRGNKA SDKATIMAFD
400 401
ALVTFCEELG CRHAAIAKYF GDALPACAKG CDHCQNPTAV RRRLEALERS
450 451
SSWSKTCIGP SQGNGFDPEL YEGGRKGYGD FSRYDEGSGG SGDEGRDEAH
500 501
KREWNLFYQK QMQLRKGKDP KIEEFVPPDE NCPLKEASSR RIPRLTVKAR
550 551
EHCLRLLEEA LSSNRQSTRT ADEADLRAKA VELEHETFRN AKVANLYKAS
600 601
VLKKVADIHR ASKDGQPYDM GGSAKSCSAQ AEPPEPNEYD IPPASHVYSL
650 651
KPKRVGAGFP KGSCPFQTAT ELMETTRIRE QAPQPERGGE HEPPSRPCGL
700 701
LDEDGSEPLP GPRGEVPGGS AHYGGPSPEK KAKSSSGGSS LAKGRASKKQ
750 751
QLLATAAHKD SQSIARFFCR RVESPALLAS APEAEGACPS CEGVQGPPMA
800 801
PEKYTGEEDG AGGHSPAPPQ TEECLRERPS TCPPRDQGTP EVQPTPAKDT
850 851
WKGKRPRSQQ ENPESQPQKR PRPSAKPSVV AEVKGSVSAS EQGTLNPTAQ
900 901
DPFQLSAPGV SLKEAANVVV KCLTPFYKEG KFASKELFKG FARHLSHLLT
950 951
QKTSPGRSVK EEAQNLIRHF FHGRARCESE ADWHGLCGPQ R
991
Show the unformatted sequence. |
| Checksums: |
CRC64:983668133DED865A
MD5:931916f5bf85664fb5881f8f81eeaae6
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
