Summary
This is the summary of UniProt entry TFE2_MOUSE (P15806).
| Description: | Transcription factor E2-alpha |
| Source organism: |
Mus musculus (Mouse)
(NCBI taxonomy ID
10090)
View Pfam proteome data. |
| Length: | 651 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam B | Pfam-B_90281 | 1 | 98 |
| disorder | n/a | 1 | 15 |
| disorder | n/a | 34 | 100 |
| low_complexity | n/a | 55 | 73 |
| disorder | n/a | 105 | 114 |
| disorder | n/a | 123 | 142 |
| low_complexity | n/a | 125 | 148 |
| disorder | n/a | 144 | 203 |
| disorder | n/a | 212 | 216 |
| disorder | n/a | 227 | 279 |
| low_complexity | n/a | 241 | 264 |
| disorder | n/a | 284 | 289 |
| disorder | n/a | 291 | 326 |
| disorder | n/a | 329 | 335 |
| low_complexity | n/a | 339 | 354 |
| disorder | n/a | 340 | 389 |
| disorder | n/a | 391 | 403 |
| disorder | n/a | 408 | 557 |
| low_complexity | n/a | 461 | 479 |
| low_complexity | n/a | 494 | 505 |
| low_complexity | n/a | 527 | 538 |
| Pfam A | HLH | 547 | 600 |
| disorder | n/a | 560 | 561 |
| disorder | n/a | 571 | 575 |
| disorder | n/a | 607 | 615 |
| disorder | n/a | 619 | 620 |
| disorder | n/a | 626 | 632 |
| disorder | n/a | 634 | 651 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P15806. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MMNQSQRMAP VGSDKELSDL LDFSMMFPLP VANGKSRPAS LGGTQFAGSG
50 51
LEDRPSSGSW GSSDQNSSSF DPSRTYSEGA HFSDSHSSLP PSTFLGAGLG
100 101
GKGSERNAYA TFGRDTSVGT LSQAGFLPGE LSLSSPGPLS PSGIKSSSQY
150 151
YPSFPSNPRR RAADGGLDTQ PKKVRKVPPG LPSSVYPPSS GDSYSRDAAA
200 201
YPSAKTPSSA YPSPFYVADG SLHPSAELWS TPSQVGFGPM LGDGSSPLPL
250 251
APGSSSVGSG TFGGLQQQDR MGYQLHGSEV NGSLPAVSSF SAAPGTYSGT
300 301
SGHTPPVSGA AAESLLGTRG TTASSSGDAL GKALASIYSP DHSSNNFSPS
350 351
PSTPVGSPQG LPGTSQWPRA GAPSALSPNY DAGLHGLSKM EDRLDEAIHV
400 401
LRSHAVGTAS DLHGLLPGHG ALTTSFTGPM SLGGRHAGLV GGSHPEEGLT
450 451
SGASLLHNHA SLPSQPSSLP DLSQRPPDSY SGLGRAGTTA GASEIKREEK
500 501
EDEEIASVAD AEEDKKDLKV PRTRTSPDED EDDLLPPEQK AEREKERRVA
550 551
NNARERLRVR DINEAFKELG RMCQLHLSSE KPQTKLLILH QAVAVILSLE
600 601
QQVRERNLNP KAACLKRREE EKVSGVVGDP QLALSAAHPG LGEAHNPAGH
650 651
L
651
Show the unformatted sequence. |
| Checksums: |
CRC64:7904ABB37B8D39CB
MD5:84c892ea5bf10223680c08e69af734e1
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| HLH | 547 - 600 | 2QL2 | A | 543 - 596 | Jmol AstexViewer SPICE |
| C | 543 - 596 | Jmol AstexViewer SPICE |
