Summary
This is the summary of UniProt entry IP3KB_HUMAN (P27987).
| Description: | Inositol-trisphosphate 3-kinase B EC=2.7.1.127 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 946 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam B | Pfam-B_34171 | 1 | 77 |
| disorder | n/a | 16 | 46 |
| low_complexity | n/a | 22 | 37 |
| disorder | n/a | 52 | 140 |
| low_complexity | n/a | 69 | 105 |
| Pfam B | Pfam-B_34168 | 78 | 222 |
| disorder | n/a | 142 | 295 |
| low_complexity | n/a | 154 | 163 |
| low_complexity | n/a | 174 | 187 |
| disorder | n/a | 299 | 562 |
| low_complexity | n/a | 358 | 370 |
| low_complexity | n/a | 445 | 458 |
| disorder | n/a | 567 | 600 |
| low_complexity | n/a | 599 | 622 |
| disorder | n/a | 606 | 636 |
| disorder | n/a | 638 | 639 |
| Pfam A | IPK | 726 | 937 |
| disorder | n/a | 770 | 791 |
| disorder | n/a | 822 | 829 |
| disorder | n/a | 838 | 839 |
| disorder | n/a | 907 | 917 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P27987. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MAVYCYALNS LVIMNSANEM KSGGGPGPSG SETPPPPRRA VLSPGSVFSP
50 51
GRGASFLFPP AESLSPEEPR SPGGWRSGRR RLNSSSGSGS GSSGSSVSSP
100 101
SWAGRLRGDR QQVVAAGTLS PPGPEEAKRK LRILQRELQN VQVNQKVGMF
150 151
EAHIQAQSSA IQAPRSPRLG RARSPSPCPF RSSSQPPGRV LVQGARSEER
200 201
RTKSWGEQCP ETSGTDSGRK GGPSLCSSQV KKGMPPLPGR AAPTGSEAQG
250 251
PSAFVRMEKG IPASPRCGSP TAMEIDKRGS PTPGTRSCLA PSLGLFGASL
300 301
TMATEVAARV TSTGPHRPQD LALTEPSGRA RELEDLQPPE ALVERQGQFL
350 351
GSETSPAPER GGPRDGEPPG KMGKGYLPCG MPGSGEPEVG KRPEETTVSV
400 401
QSAESSDSLS WSRLPRALAS VGPEEARSGA PVGGGRWQLS DRVEGGSPTL
450 451
GLLGGSPSAQ PGTGNVEAGI PSGRMLEPLP CWDAAKDLKE PQCPPGDRVG
500 501
VQPGNSRVWQ GTMEKAGLAW TRGTGVQSEG TWESQRQDSD ALPSPELLPQ
550 551
DPDKPFLRKA CSPSNIPAVI ITDMGTQEDG ALEETQGSPR GNLPLRKLSS
600 601
SSASSTGFSS SYEDSEEDIS SDPERTLDPN SAFLHTLDQQ KPRVSKSWRK
650 651
IKNMVHWSPF VMSFKKKYPW IQLAGHAGSF KAAANGRILK KHCESEQRCL
700 701
DRLMVDVLRP FVPAYHGDVV KDGERYNQMD DLLADFDSPC VMDCKMGIRT
750 751
YLEEELTKAR KKPSLRKDMY QKMIEVDPEA PTEEEKAQRA VTKPRYMQWR
800 801
ETISSTATLG FRIEGIKKED GTVNRDFKKT KTREQVTEAF REFTKGNHNI
850 851
LIAYRDRLKA IRTTLEVSPF FKCHEVIGSS LLFIHDKKEQ AKVWMIDFGK
900 901
TTPLPEGQTL QHDVPWQEGN REDGYLSGLN NLVDILTEMS QDAPLA
946
Show the unformatted sequence. |
| Checksums: |
CRC64:2CCBCBE7AEF26848
MD5:1c678b24c1bfeccac57a9881405a90aa
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
