Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PDX1_HUMAN (P52945)

Summary

This is the summary of UniProt entry PDX1_HUMAN (P52945).

Description: Pancreas/duodenum homeobox protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 283 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 2
disorder n/a 5 6
disorder n/a 19 23
disorder n/a 31 74
low_complexity n/a 42 51
low_complexity n/a 73 107
disorder n/a 76 82
disorder n/a 84 88
disorder n/a 90 109
disorder n/a 111 116
disorder n/a 133 154
Pfam A Homeobox 147 203
low_complexity n/a 158 167
disorder n/a 201 283
low_complexity n/a 210 221
low_complexity n/a 236 256

Show or hide domain scores.

Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

Note: it can take a few seconds for this image to be generated and loaded.

Loading feature alignment...

Show sources update panel.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P52945. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNGEEQYYAA TQLYKDPCAF QRGPAPEFSA SPPACLYMGR QPPPPPPHPF
50
51
PGALGALEQG SPPDISPYEV PPLADDPAVA HLHHHLPAQL ALPHPPAGPF
100
101
PEGAEPGVLE EPNRVQLPFP WMKSTKAHAW KGQWAGGAYA AEPEENKRTR
150
151
TAYTRAQLLE LEKEFLFNKY ISRPRRVELA VMLNLTERHI KIWFQNRRMK
200
201
WKKEEDKKRG GGTAVGGGGV AEPEQDCAVT SGEELLALPP PPPPGGAVPP
250
251
AAPVAAREGR LPPGLSASPQ PSSVAPRRPQ EPR                  
283
 

Show the unformatted sequence.

Checksums:
CRC64:5D48EC8D3289F72B
MD5:89e76b156357f6ff0eecfb8df7e5469a

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.