Summary
This is the summary of UniProt entry S12A2_HUMAN (P55011).
| Description: | Solute carrier family 12 member 2 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 1212 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 88 |
| low_complexity | n/a | 24 | 30 |
| low_complexity | n/a | 90 | 113 |
| disorder | n/a | 97 | 98 |
| disorder | n/a | 105 | 197 |
| low_complexity | n/a | 147 | 160 |
| low_complexity | n/a | 182 | 209 |
| Pfam A | AA_permease_N | 201 | 269 |
| disorder | n/a | 254 | 263 |
| disorder | n/a | 270 | 271 |
| Pfam A | AA_permease | 290 | 793 |
| transmembrane | n/a | 291 | 311 |
| transmembrane | n/a | 317 | 343 |
| low_complexity | n/a | 321 | 334 |
| transmembrane | n/a | 364 | 388 |
| transmembrane | n/a | 408 | 427 |
| transmembrane | n/a | 436 | 457 |
| low_complexity | n/a | 436 | 444 |
| transmembrane | n/a | 487 | 509 |
| transmembrane | n/a | 521 | 541 |
| transmembrane | n/a | 602 | 622 |
| low_complexity | n/a | 609 | 622 |
| transmembrane | n/a | 655 | 675 |
| transmembrane | n/a | 681 | 699 |
| transmembrane | n/a | 711 | 730 |
| transmembrane | n/a | 736 | 751 |
| disorder | n/a | 934 | 940 |
| disorder | n/a | 967 | 989 |
| disorder | n/a | 1119 | 1120 |
| disorder | n/a | 1125 | 1127 |
| Pfam B | Pfam-B_1574 | 1145 | 1181 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P55011. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MEPRPTAPSS GAPGLAGVGE TPSAAALAAA RVELPGTAVP SVPEDAAPAS
50 51
RDGGGVRDEG PAAAGDGLGR PLGPTPSQSR FQVDLVSENA GRAAAAAAAA
100 101
AAAAAAAGAG AGAKQTPADG EASGESEPAK GSEEAKGRFR VNFVDPAASS
150 151
SAEDSLSDAA GVGVDGPNVS FQNGGDTVLS EGSSLHSGGG GGSGHHQHYY
200 201
YDTHTNTYYL RTFGHNTMDA VPRIDHYRHT AAQLGEKLLR PSLAELHDEL
250 251
EKEPFEDGFA NGEESTPTRD AVVTYTAESK GVVKFGWIKG VLVRCMLNIW
300 301
GVMLFIRLSW IVGQAGIGLS VLVIMMATVV TTITGLSTSA IATNGFVRGG
350 351
GAYYLISRSL GPEFGGAIGL IFAFANAVAV AMYVVGFAET VVELLKEHSI
400 401
LMIDEINDIR IIGAITVVIL LGISVAGMEW EAKAQIVLLV ILLLAIGDFV
450 451
IGTFIPLESK KPKGFFGYKS EIFNENFGPD FREEETFFSV FAIFFPAATG
500 501
ILAGANISGD LADPQSAIPK GTLLAILITT LVYVGIAVSV GSCVVRDATG
550 551
NVNDTIVTEL TNCTSAACKL NFDFSSCESS PCSYGLMNNF QVMSMVSGFT
600 601
PLISAGIFSA TLSSALASLV SAPKIFQALC KDNIYPAFQM FAKGYGKNNE
650 651
PLRGYILTFL IALGFILIAE LNVIAPIISN FFLASYALIN FSVFHASLAK
700 701
SPGWRPAFKY YNMWISLLGA ILCCIVMFVI NWWAALLTYV IVLGLYIYVT
750 751
YKKPDVNWGS STQALTYLNA LQHSIRLSGV EDHVKNFRPQ CLVMTGAPNS
800 801
RPALLHLVHD FTKNVGLMIC GHVHMGPRRQ AMKEMSIDQA KYQRWLIKNK
850 851
MKAFYAPVHA DDLREGAQYL MQAAGLGRMK PNTLVLGFKK DWLQADMRDV
900 901
DMYINLFHDA FDIQYGVVVI RLKEGLDISH LQGQEELLSS QEKSPGTKDV
950 951
VVSVEYSKKS DLDTSKPLSE KPITHKVEEE DGKTATQPLL KKESKGPIVP
1000 1001
LNVADQKLLE ASTQFQKKQG KNTIDVWWLF DDGGLTLLIP YLLTTKKKWK
1050 1051
DCKIRVFIGG KINRIDHDRR AMATLLSKFR IDFSDIMVLG DINTKPKKEN
1100 1101
IIAFEEIIEP YRLHEDDKEQ DIADKMKEDE PWRITDNELE LYKTKTYRQI
1150 1151
RLNELLKEHS STANIIVMSL PVARKGAVSS ALYMAWLEAL SKDLPPILLV
1200 1201
RGNHQSVLTF YS
1212
Show the unformatted sequence. |
| Checksums: |
CRC64:A6BF174ACCDA2EC1
MD5:ee6c6ee7346eb47bd82076f48c9ea963
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
