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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: M4K1_MOUSE (P70218)

Summary

This is the summary of UniProt entry M4K1_MOUSE (P70218).

Description: Mitogen-activated protein kinase kinase kinase kinase 1 EC=2.7.11.1
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 827 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Pkinase 17 274
disorder n/a 261 262
disorder n/a 264 271
disorder n/a 295 321
low_complexity n/a 301 318
disorder n/a 332 333
disorder n/a 344 346
disorder n/a 356 485
low_complexity n/a 373 383
low_complexity n/a 385 416
low_complexity n/a 426 446
disorder n/a 508 509
Pfam A CNH 511 803
disorder n/a 515 516
low_complexity n/a 655 672
disorder n/a 741 743
disorder n/a 745 752
disorder n/a 809 826

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P70218. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MALVDPDIFN KDPREHYDLL QRLGGGTYGE VFKARDKVSK DLVALKMVKM
50
51
EPDDDVATLQ KEILMLKTCR HANIVAYHGS YLWLQKLWIC MEFCGAGSLQ
100
101
DIYQVTGSLS ELQISYVCRE VLQGLAYLHS EKKIHRDIKG ANILINDCGE
150
151
VKLADFGISA QIGATLARRL SFIGTPYWMA PEVAAVALKG GYNELCDIWS
200
201
LGITAIELAE LQPPLFDVHP LRVLFLMTKS GYQPPRLKEK SRWSSSFHNF
250
251
VKVTLTKNSK KRPSATKMLS HQLVSQPGLN RGLILDLLDK MKNPGKGLPV
300
301
DIEDEEPEPP PAIPRRIRST YRASSLGIPD ADCCRRQMEF QRPRCVDCRP
350
351
QAETVRLYPP AHFGSTSPRS QLSDSDDDYD DVDIPAPSEN IPPPLPPKPK
400
401
FRSPSDDGSG GIRDDGQLSP GVLVRCASGP PPRTPRPGPP PATCSPHLTA
450
451
RSDPSLWNPA APEPGQPPLV PPRKEKMRGK MENEKRREKY PLLVKLFNGC
500
501
PLQIHSTAAW THPSTKDQNL LLGAEEGIFI LNRNDQEATL EMIFPGRTTW
550
551
LYCINNLLMS LSGKTPYLYS HSILGLLERK DGRTGSPIAH ISPHRLLARK
600
601
NMVSSKIQDT KGCRACCVAE SASSGGPFLC GALETSVVLL QWYQPMNKFL
650
651
LVRQVLFPLP TPLPVFTLLT TPGSELPAVC IGVSPGQAAK SVLFHTVRFG
700
701
ALSCWLDDSS TEHKGPVQVI QVKEDMVMVL MDGSLKLVTP EGAPAPGLRT
750
751
PEIPMTEAVE AVAMVEDRLE AFWKHGVQVW APGLKQPLQE LRDPTLTFRL
800
801
LCSPRPVVVE TRPTDDPTAP SNLYIQE                         
827
 

Show the unformatted sequence.

Checksums:
CRC64:82341BE9D13036BA
MD5:7ab122c5b8422bff61a9343a8a067bf0

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.