Summary
This is the summary of UniProt entry EPS8_HUMAN (Q12929).
| Description: | Epidermal growth factor receptor kinase substrate 8 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 822 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 3 |
| disorder | n/a | 5 | 10 |
| disorder | n/a | 12 | 17 |
| disorder | n/a | 23 | 44 |
| Pfam A | PTB | 64 | 194 |
| low_complexity | n/a | 176 | 187 |
| disorder | n/a | 182 | 227 |
| low_complexity | n/a | 210 | 221 |
| low_complexity | n/a | 229 | 241 |
| disorder | n/a | 245 | 265 |
| disorder | n/a | 295 | 320 |
| low_complexity | n/a | 299 | 310 |
| disorder | n/a | 467 | 479 |
| disorder | n/a | 508 | 513 |
| disorder | n/a | 515 | 517 |
| disorder | n/a | 520 | 530 |
| disorder | n/a | 536 | 540 |
| Pfam A | SH3_1 | 537 | 582 |
| disorder | n/a | 554 | 555 |
| disorder | n/a | 571 | 572 |
| disorder | n/a | 579 | 699 |
| low_complexity | n/a | 615 | 652 |
| low_complexity | n/a | 659 | 667 |
| disorder | n/a | 701 | 707 |
| disorder | n/a | 715 | 722 |
| disorder | n/a | 734 | 735 |
| disorder | n/a | 788 | 801 |
| disorder | n/a | 807 | 822 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q12929. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MNGHISNHPS SFGMYPSQMN GYGSSPTFSQ TDREHGSKTS AKALYEQRKN
50 51
YARDSVSSVS DISQYRVEHL TTFVLDRKDA MITVDDGIRK LKLLDAKGKV
100 101
WTQDMILQVD DRAVSLIDLE SKNELENFPL NTIQHCQAVM HSCSYDSVLA
150 151
LVCKEPTQNK PDLHLFQCDE VKANLISEDI ESAISDSKGG KQKRRPDALR
200 201
MISNADPSIP PPPRAPAPAP PGTVTQVDVR SRVAAWSAWA ADQGDFEKPR
250 251
QYHEQEETPE MMAARIDRDV QILNHILDDI EFFITKLQKA AEAFSELSKR
300 301
KKNKKGKRKG PGEGVLTLRA KPPPPDEFLD CFQKFKHGFN LLAKLKSHIQ
350 351
NPSAADLVHF LFTPLNMVVQ ATGGPELASS VLSPLLNKDT IDFLNYTVNG
400 401
DERQLWMSLG GTWMKARAEW PKEQFIPPYV PRFRNGWEPP MLNFMGATME
450 451
QDLYQLAESV ANVAEHQRKQ EIKRLSTEHS SVSEYHPADG YAFSSNIYTR
500 501
GSHLDQGEAA VAFKPTSNRH IDRNYEPLKT QPKKYAKSKY DFVARNNSEL
550 551
SVLKDDILEI LDDRKQWWKV RNASGDSGFV PNNILDIVRP PESGLGRADP
600 601
PYTHTIQKQR MEYGPRPADT PPAPSPPPTP APVPVPLPPS TPAPVPVSKV
650 651
PANITRQNSS SSDSGGSIVR DSQRHKQLPV DRRKSQMEEV QDELIHRLTI
700 701
GRSAAQKKFH VPRQNVPVIN ITYDSTPEDV KTWLQSKGFN PVTVNSLGVL
750 751
NGAQLFSLNK DELRTVCPEG ARVYSQITVQ KAALEDSSGS SELQEIMRRR
800 801
QEKISAAASD SGVESFDEGS SH
822
Show the unformatted sequence. |
| Checksums: |
CRC64:AC5EB1D28B784B3B
MD5:737da549563b46e1aeca9ae35bfa47df
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
