Summary
This is the summary of UniProt entry FAT1_HUMAN (Q14517).
| Description: | Protocadherin Fat 1 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 4588 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 19 |
| low_complexity | n/a | 5 | 14 |
| Pfam A | Cadherin | 154 | 248 |
| Pfam A | Cadherin | 468 | 560 |
| disorder | n/a | 483 | 485 |
| Pfam B | Pfam-B_13463 | 654 | 721 |
| Pfam A | Cadherin | 722 | 813 |
| Pfam A | Cadherin | 827 | 918 |
| disorder | n/a | 842 | 845 |
| disorder | n/a | 855 | 856 |
| disorder | n/a | 890 | 896 |
| disorder | n/a | 898 | 899 |
| disorder | n/a | 930 | 933 |
| Pfam A | Cadherin | 932 | 1023 |
| disorder | n/a | 960 | 962 |
| low_complexity | n/a | 1018 | 1028 |
| Pfam A | Cadherin | 1039 | 1130 |
| disorder | n/a | 1054 | 1057 |
| disorder | n/a | 1065 | 1069 |
| disorder | n/a | 1093 | 1095 |
| disorder | n/a | 1136 | 1147 |
| Pfam A | Cadherin | 1144 | 1236 |
| disorder | n/a | 1159 | 1162 |
| disorder | n/a | 1172 | 1175 |
| disorder | n/a | 1189 | 1191 |
| disorder | n/a | 1197 | 1220 |
| disorder | n/a | 1228 | 1233 |
| disorder | n/a | 1249 | 1250 |
| disorder | n/a | 1256 | 1277 |
| Pfam A | Cadherin | 1261 | 1344 |
| disorder | n/a | 1283 | 1290 |
| disorder | n/a | 1338 | 1341 |
| disorder | n/a | 1343 | 1344 |
| Pfam A | Cadherin | 1363 | 1447 |
| disorder | n/a | 1424 | 1426 |
| disorder | n/a | 1458 | 1463 |
| Pfam A | Cadherin | 1461 | 1553 |
| disorder | n/a | 1475 | 1478 |
| Pfam A | Cadherin | 1567 | 1658 |
| disorder | n/a | 1635 | 1638 |
| Pfam A | Cadherin | 1672 | 1756 |
| Pfam A | Cadherin | 1775 | 1868 |
| Pfam A | Cadherin | 1891 | 1970 |
| Pfam A | Cadherin | 1984 | 2072 |
| disorder | n/a | 2034 | 2037 |
| low_complexity | n/a | 2062 | 2071 |
| Pfam A | Cadherin | 2086 | 2175 |
| Pfam A | Cadherin | 2187 | 2274 |
| low_complexity | n/a | 2269 | 2282 |
| Pfam A | Cadherin | 2288 | 2381 |
| disorder | n/a | 2308 | 2310 |
| disorder | n/a | 2316 | 2321 |
| low_complexity | n/a | 2370 | 2386 |
| Pfam A | Cadherin | 2395 | 2483 |
| Pfam A | Cadherin | 2497 | 2587 |
| Pfam A | Cadherin | 2601 | 2694 |
| Pfam A | Cadherin | 2708 | 2800 |
| disorder | n/a | 2738 | 2739 |
| disorder | n/a | 2747 | 2750 |
| Pfam A | Cadherin | 2814 | 2909 |
| disorder | n/a | 2830 | 2834 |
| disorder | n/a | 2840 | 2845 |
| disorder | n/a | 2883 | 2884 |
| disorder | n/a | 2919 | 2925 |
| Pfam A | Cadherin | 2923 | 3014 |
| disorder | n/a | 2935 | 2942 |
| Pfam A | Cadherin | 3028 | 3116 |
| disorder | n/a | 3073 | 3084 |
| Pfam A | Cadherin | 3130 | 3221 |
| disorder | n/a | 3146 | 3147 |
| Pfam A | Cadherin | 3235 | 3326 |
| low_complexity | n/a | 3317 | 3332 |
| Pfam A | Cadherin | 3340 | 3431 |
| disorder | n/a | 3368 | 3371 |
| disorder | n/a | 3408 | 3428 |
| Pfam A | Cadherin | 3445 | 3536 |
| disorder | n/a | 3475 | 3476 |
| Pfam A | Laminin_G_2 | 3859 | 3985 |
| disorder | n/a | 3963 | 3964 |
| Pfam A | EGF | 4017 | 4048 |
| Pfam A | EGF | 4093 | 4123 |
| Pfam A | EGF_CA | 4127 | 4168 |
| transmembrane | n/a | 4182 | 4202 |
| Pfam B | Pfam-B_9821 | 4199 | 4377 |
| disorder | n/a | 4212 | 4221 |
| disorder | n/a | 4253 | 4275 |
| disorder | n/a | 4279 | 4280 |
| disorder | n/a | 4284 | 4290 |
| disorder | n/a | 4298 | 4327 |
| low_complexity | n/a | 4306 | 4322 |
| disorder | n/a | 4329 | 4330 |
| disorder | n/a | 4341 | 4371 |
| disorder | n/a | 4373 | 4376 |
| disorder | n/a | 4379 | 4380 |
| disorder | n/a | 4382 | 4385 |
| disorder | n/a | 4387 | 4388 |
| disorder | n/a | 4393 | 4394 |
| disorder | n/a | 4397 | 4481 |
| Pfam B | Pfam-B_7840 | 4416 | 4448 |
| low_complexity | n/a | 4435 | 4455 |
| disorder | n/a | 4495 | 4528 |
| disorder | n/a | 4530 | 4532 |
| Pfam B | Pfam-B_3438 | 4556 | 4586 |
| disorder | n/a | 4557 | 4560 |
| disorder | n/a | 4563 | 4588 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q14517. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MGRHLALLLL LLLLFQHFGD SDGSQRLEQT PLQFTHLEYN VTVQENSAAK
50 51
TYVGHPVKMG VYITHPAWEV RYKIVSGDSE NLFKAEEYIL GDFCFLRIRT
100 101
KGGNTAILNR EVKDHYTLIV KALEKNTNVE ARTKVRVQVL DTNDLRPLFS
150 151
PTSYSVSLPE NTAIRTSIAR VSATDADIGT NGEFYYSFKD RTDMFAIHPT
200 201
SGVIVLTGRL DYLETKLYEM EILAADRGMK LYGSSGISSM AKLTVHIEQA
250 251
NECAPVITAV TLSPSELDRD PAYAIVTVDD CDQGANGDIA SLSIVAGDLL
300 301
QQFRTVRSFP GSKEYKVKAI GGIDWDSHPF GYNLTLQAKD KGTPPQFSSV
350 351
KVIHVTSPQF KAGPVKFEKD VYRAEISEFA PPNTPVVMVK AIPAYSHLRY
400 401
VFKSTPGKAK FSLNYNTGLI SILEPVKRQQ AAHFELEVTT SDRKASTKVL
450 451
VKVLGANSNP PEFTQTAYKA AFDENVPIGT TVMSLSAVDP DEGENGYVTY
500 501
SIANLNHVPF AIDHFTGAVS TSENLDYELM PRVYTLRIRA SDWGLPYRRE
550 551
VEVLATITLN NLNDNTPLFE KINCEGTIPR DLGVGEQITT VSAIDADELQ
600 601
LVQYQIEAGN ELDFFSLNPN SGVLSLKRSL MDGLGAKVSF HSLRITATDG
650 651
ENFATPLYIN ITVAASHKLV NLQCEETGVA KMLAEKLLQA NKLHNQGEVE
700 701
DIFFDSHSVN AHIPQFRSTL PTGIQVKENQ PVGSSVIFMN STDLDTGFNG
750 751
KLVYAVSGGN EDSCFMIDME TGMLKILSPL DRETTDKYTL NITVYDLGIP
800 801
QKAAWRLLHV VVVDANDNPP EFLQESYFVE VSEDKEVHSE IIQVEATDKD
850 851
LGPNGHVTYS IVTDTDTFSI DSVTGVVNIA RPLDRELQHE HSLKIEARDQ
900 901
AREEPQLFST VVVKVSLEDV NDNPPTFIPP NYRVKVREDL PEGTVIMWLE
950 951
AHDPDLGQSG QVRYSLLDHG EGNFDVDKLS GAVRIVQQLD FEKKQVYNLT
1000 1001
VRAKDKGKPV SLSSTCYVEV EVVDVNENLH PPVFSSFVEK GTVKEDAPVG
1050 1051
SLVMTVSAHD EDARRDGEIR YSIRDGSGVG VFKIGEETGV IETSDRLDRE
1100 1101
STSHYWLTVF ATDQGVVPLS SFIEIYIEVE DVNDNAPQTS EPVYYPEIME
1150 1151
NSPKDVSVVQ IEAFDPDSSS NDKLMYKITS GNPQGFFSIH PKTGLITTTS
1200 1201
RKLDREQQDE HILEVTVTDN GSPPKSTIAR VIVKILDEND NKPQFLQKFY
1250 1251
KIRLPEREKP DRERNARREP LYHVIATDKD EGPNAEISYS IEDGNEHGKF
1300 1301
FIEPKTGVVS SKRFSAAGEY DILSIKAVDN GRPQKSSTTR LHIEWISKPK
1350 1351
PSLEPISFEE SFFTFTVMES DPVAHMIGVI SVEPPGIPLW FDITGGNYDS
1400 1401
HFDVDKGTGT IIVAKPLDAE QKSNYNLTVE ATDGTTTILT QVFIKVIDTN
1450 1451
DHRPQFSTSK YEVVIPEDTA PETEILQISA VDQDEKNKLI YTLQSSRDPL
1500 1501
SLKKFRLDPA TGSLYTSEKL DHEAVHQHTL TVMVRDQDVP VKRNFARIVV
1550 1551
NVSDTNDHAP WFTASSYKGR VYESAAVGSV VLQVTALDKD KGKNAEVLYS
1600 1601
IESGNIGNSF MIDPVLGSIK TAKELDRSNQ AEYDLMVKAT DKGSPPMSEI
1650 1651
TSVRIFVTIA DNASPKFTSK EYSVELSETV SIGSFVGMVT AHSQSSVVYE
1700 1701
IKDGNTGDAF DINPHSGTII TQKALDFETL PIYTLIIQGT NMAGLSTNTT
1750 1751
VLVHLQDEND NAPVFMQAEY TGLISESASI NSVVLTDRNV PLVIRAADAD
1800 1801
KDSNALLVYH IVEPSVHTYF AIDSSTGAIH TVLSLDYEET SIFHFTVQVH
1850 1851
DMGTPRLFAE YAANVTVHVI DINDCPPVFA KPLYEASLLL PTYKGVKVIT
1900 1901
VNATDADSSA FSQLIYSITE GNIGEKFSMD YKTGALTVQN TTQLRSRYEL
1950 1951
TVRASDGRFA GLTSVKINVK ESKESHLKFT QDVYSAVVKE NSTEAETLAV
2000 2001
ITAIGNPINE PLFYHILNPD RRFKISRTSG VLSTTGTPFD REQQEAFDVV
2050 2051
VEVTEEHKPS AVAHVVVKVI VEDQNDNAPV FVNLPYYAVV KVDTEVGHVI
2100 2101
RYVTAVDRDS GRNGEVHYYL KEHHEHFQIG PLGEISLKKQ FELDTLNKEY
2150 2151
LVTVVAKDGG NPAFSAEVIV PITVMNKAMP VFEKPFYSAE IAESIQVHSP
2200 2201
VVHVQANSPE GLKVFYSITD GDPFSQFTIN FNTGVINVIA PLDFEAHPAY
2250 2251
KLSIRATDSL TGAHAEVFVD IIVDDINDNP PVFAQQSYAV TLSEASVIGT
2300 2301
SVVQVRATDS DSEPNRGISY QMFGNHSKSH DHFHVDSSTG LISLLRTLDY
2350 2351
EQSRQHTIFV RAVDGGMPTL SSDVIVTVDV TDLNDNPPLF EQQIYEARIS
2400 2401
EHAPHGHFVT CVKAYDADSS DIDKLQYSIL SGNDHKHFVI DSATGIITLS
2450 2451
NLHRHALKPF YSLNLSVSDG VFRSSTQVHV TVIGGNLHSP AFLQNEYEVE
2500 2501
LAENAPLHTL VMEVKTTDGD SGIYGHVTYH IVNDFAKDRF YINERGQIFT
2550 2551
LEKLDRETPA EKVISVRLMA KDAGGKVAFC TVNVILTDDN DNAPQFRATK
2600 2601
YEVNIGSSAA KGTSVVKVLA SDADEGSNAD ITYAIEADSE SVKENLEINK
2650 2651
LSGVITTKES LIGLENEFFT FFVRAVDNGS PSKESVVLVY VKILPPEMQL
2700 2701
PKFSEPFYTF TVSEDVPIGT EIDLIRAEHS GTVLYSLVKG NTPESNRDES
2750 2751
FVIDRQSGRL KLEKSLDHET TKWYQFSILA RCTQDDHEMV ASVDVSIQVK
2800 2801
DANDNSPVFE SSPYEAFIVE NLPGGSRVIQ IRASDADSGT NGQVMYSLDQ
2850 2851
SQSVEVIESF AINMETGWIT TLKELDHEKR DNYQIKVVAS DHGEKIQLSS
2900 2901
TAIVDVTVTD VNDSPPRFTA EIYKGTVSED DPQGGVIAIL STTDADSEEI
2950 2951
NRQVTYFITG GDPLGQFAVE TIQNEWKVYV KKPLDREKRD NYLLTITATD
3000 3001
GTFSSKAIVE VKVLDANDNS PVCEKTLYSD TIPEDVLPGK LIMQISATDA
3050 3051
DIRSNAEITY TLLGSGAEKF KLNPDTGELK TSTPLDREEQ AVYHLLVRAT
3100 3101
DGGGRFCQAS IVLTLEDVND NAPEFSADPY AITVFENTEP GTLLTRVQAT
3150 3151
DADAGLNRKI LYSLIDSADG QFSINELSGI IQLEKPLDRE LQAVYTLSLK
3200 3201
AVDQGLPRRL TATGTVIVSV LDINDNPPVF EYREYGATVS EDILVGTEVL
3250 3251
QVYAASRDIE ANAEITYSII SGNEHGKFSI DSKTGAVFII ENLDYESSHE
3300 3301
YYLTVEATDG GTPSLSDVAT VNVNVTDIND NTPVFSQDTY TTVISEDAVL
3350 3351
EQSVITVMAD DADGPSNSHI HYSIIDGNQG SSFTIDPVRG EVKVTKLLDR
3400 3401
ETISGYTLTV QASDNGSPPR VNTTTVNIDV SDVNDNAPVF SRGNYSVIIQ
3450 3451
ENKPVGFSVL QLVVTDEDSS HNGPPFFFTI VTGNDEKAFE VNPQGVLLTS
3500 3501
SAIKRKEKDH YLLQVKVADN GKPQLSSLTY IDIRVIEESI YPPAILPLEI
3550 3551
FITSSGEEYS GGVIGKIHAT DQDVYDTLTY SLDPQMDNLF SVSSTGGKLI
3600 3601
AHKKLDIGQY LLNVSVTDGK FTTVADITVH IRQVTQEMLN HTIAIRFANL
3650 3651
TPEEFVGDYW RNFQRALRNI LGVRRNDIQI VSLQSSEPHP HLDVLLFVEK
3700 3701
PGSAQISTKQ LLHKINSSVT DIEEIIGVRI LNVFQKLCAG LDCPWKFCDE
3750 3751
KVSVDESVMS THSTARLSFV TPRHHRAAVC LCKEGRCPPV HHGCEDDPCP
3800 3801
EGSECVSDPW EEKHTCVCPS GRFGQCPGSS SMTLTGNSYV KYRLTENENK
3850 3851
LEMKLTMRLR TYSTHAVVMY ARGTDYSILE IHHGRLQYKF DCGSGPGIVS
3900 3901
VQSIQVNDGQ WHAVALEVNG NYARLVLDQV HTASGTAPGT LKTLNLDNYV
3950 3951
FFGGHIRQQG TRHGRSPQVG NGFRGCMDSI YLNGQELPLN SKPRSYAHIE
4000 4001
ESVDVSPGCF LTATEDCASN PCQNGGVCNP SPAGGYYCKC SALYIGTHCE
4050 4051
ISVNPCSSKP CLYGGTCVVD NGGFVCQCRG LYTGQRCQLS PYCKDEPCKN
4100 4101
GGTCFDSLDG AVCQCDSGFR GERCQSDIDE CSGNPCLHGA LCENTHGSYH
4150 4151
CNCSHEYRGR HCEDAAPNQY VSTPWNIGLA EGIGIVVFVA GIFLLVVVFV
4200 4201
LCRKMISRKK KHQAEPKDKH LGPATAFLQR PYFDSKLNKN IYSDIPPQVP
4250 4251
VRPISYTPSI PSDSRNNLDR NSFEGSAIPE HPEFSTFNPE SVHGHRKAVA
4300 4301
VCSVAPNLPP PPPSNSPSDS DSIQKPSWDF DYDTKVVDLD PCLSKKPLEE
4350 4351
KPSQPYSARE SLSEVQSLSS FQSESCDDNG YHWDTSDWMP SVPLPDIQEF
4400 4401
PNYEVIDEQT PLYSADPNAI DTDYYPGGYD IESDFPPPPE DFPAADELPP
4450 4451
LPPEFSNQFE SIHPPRDMPA AGSLGSSSRN RQRFNLNQYL PNFYPLDMSE
4500 4501
PQTKGTGENS TCREPHAPYP PGYQRHFEAP AVESMPMSVY ASTASCSDVS
4550 4551
ACCEVESEVM MSDYESGDDG HFEEVTIPPL DSQQHTEV
4588
Show the unformatted sequence. |
| Checksums: |
CRC64:1896223E46E3B892
MD5:5fbb10eb9fdb7ddb53de0619f6f948ce
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