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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: UBE2S_HUMAN (Q16763)

Summary

This is the summary of UniProt entry UBE2S_HUMAN (Q16763).

Description: Ubiquitin-conjugating enzyme E2 S EC=6.3.2.19
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 222 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A UQ_con 15 152
disorder n/a 43 47
disorder n/a 155 159
disorder n/a 161 222
low_complexity n/a 182 194
low_complexity n/a 203 222

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q16763. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNSNVENLPP HIIRLVYKEV TTLTADPPDG IKVFPNEEDL TDLQVTIEGP
50
51
EGTPYAGGLF RMKLLLGKDF PASPPKGYFL TKIFHPNVGA NGEICVNVLK
100
101
RDWTAELGIR HVLLTIKCLL IHPNPESALN EEAGRLLLEN YEEYAARARL
150
151
LTEIHGGAGG PSGRAEAGRA LASGTEASST DPGAPGGPGG AEGPMAKKHA
200
201
GERDKKLAAK KKTDKKRALR RL                              
222
 

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Checksums:
CRC64:2842DC3DCD2AFCB5
MD5:db19cd1175139db0d6501f9df7068c26

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
UQ_con 15 - 152 1ZDN A 15 - 152 Jmol AstexViewer SPICE
B 15 - 152 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.