Summary
This is the summary of UniProt entry ARHGH_MOUSE (Q80U35).
| Description: | Rho guanine nucleotide exchange factor 17 |
| Source organism: |
Mus musculus (Mouse)
(NCBI taxonomy ID
10090)
View Pfam proteome data. |
| Length: | 2057 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam B | Pfam-B_56760 | 1 | 59 |
| disorder | n/a | 1 | 365 |
| Pfam B | Pfam-B_41715 | 61 | 189 |
| low_complexity | n/a | 65 | 74 |
| low_complexity | n/a | 160 | 175 |
| Pfam B | Pfam-B_45820 | 191 | 278 |
| low_complexity | n/a | 196 | 209 |
| low_complexity | n/a | 227 | 255 |
| low_complexity | n/a | 282 | 297 |
| low_complexity | n/a | 314 | 323 |
| disorder | n/a | 367 | 373 |
| disorder | n/a | 377 | 395 |
| disorder | n/a | 416 | 461 |
| disorder | n/a | 478 | 540 |
| low_complexity | n/a | 507 | 526 |
| disorder | n/a | 542 | 544 |
| Pfam B | Pfam-B_33219 | 543 | 621 |
| disorder | n/a | 547 | 555 |
| disorder | n/a | 558 | 572 |
| low_complexity | n/a | 559 | 572 |
| disorder | n/a | 574 | 584 |
| disorder | n/a | 588 | 649 |
| disorder | n/a | 651 | 654 |
| disorder | n/a | 658 | 1055 |
| low_complexity | n/a | 828 | 842 |
| low_complexity | n/a | 970 | 984 |
| disorder | n/a | 1062 | 1063 |
| Pfam A | RhoGEF | 1063 | 1246 |
| low_complexity | n/a | 1112 | 1123 |
| disorder | n/a | 1224 | 1225 |
| disorder | n/a | 1227 | 1231 |
| Pfam B | Pfam-B_29902 | 1256 | 1324 |
| low_complexity | n/a | 1313 | 1327 |
| Pfam B | Pfam-B_2142 | 1467 | 1508 |
| disorder | n/a | 1555 | 1713 |
| low_complexity | n/a | 1582 | 1595 |
| low_complexity | n/a | 1630 | 1642 |
| low_complexity | n/a | 1646 | 1657 |
| low_complexity | n/a | 1661 | 1701 |
| low_complexity | n/a | 1708 | 1719 |
| disorder | n/a | 1718 | 1719 |
| Pfam B | Pfam-B_12344 | 1866 | 1905 |
| disorder | n/a | 1981 | 2049 |
| low_complexity | n/a | 1986 | 1990 |
| low_complexity | n/a | 2033 | 2040 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q80U35. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MADGSPRPPL YRSVSFKLLE RWSGGPGPRE EDADTPGLRR RASCRPAAAV
50 51
PGQPSRRVSK LASGPPAAPA QPRPLRSLSP SVRQLSRRFD AAGLDDDSTG
100 101
TRDGGCSSGT TEEAAEGSER GAWPSVTEMR KLFGGPSSRR PSMDSEALGS
150 151
TSPDRVSWEP PTRDPRQPPT PPPRTCFPLA GLRSARPLSG PGIEGRRRRQ
200 201
HQQQERAQRP ADGLHSWHSF SQPQAGARAS SSSSIASSYP VSRSRAASSS
250 251
EEEEEGPQSQ LGPQSPAYLG GHSSGSDEDP NGEDGRRWRG RGLRPGRSQL
300 301
VHGCSQDSDE LNPGGLGSAG GVGSPEPPTS PRTSMDEWGT GTQPCLPGPQ
350 351
ESLRPMSDTG GAPFRVAKVS FPAYLASPAG SRGSSRYSST ETLKDDDLWS
400 401
SRSSVGWGVY RSPSFGTGDG LLLRPQTRSR SKGPVGTARP LRDGGLDLDK
450 451
NRQRKSLSNP DIASETLTLL SFLRSDLSEL RVRKPSGGPG NRPLDGRDSP
500 501
SAGSPMEQSE STLSQSPTSP TTRPTLKDLT ATLRRAKSFS CSEKPMARRL
550 551
LRTSALKPSS SELLLAGSGA EEDPLPLVVQ DQYVQEARQV FEKIQRMGAQ
600 601
QDDGNDVCPT SPDWAGDMTQ GHRSQEELSG PESNLTDEGI GADPEPLGAA
650 651
FCSLDPAGVW RPLSSTSAQT NHHLGAGTED SLGGRALVSP ETPPTPGALR
700 701
RRRKVPPSGP NGTELSNGEA SEAYRSLSDP IPQRHRAATS EEPSGFSVDS
750 751
NLLGSLNSKT GLPVTPAMDE GLTSGHSDWS VVSEENKDYQ EVIQSIVQGP
800 801
GALGRMGEDR IAGKTPKKKS LSDPSRRGEL TGPGFEGPGG EPIREVEPML
850 851
PPSSSEPILA EQWTEPEDPA PARGRAQSER SLPAPPASST AHHDFHLDPK
900 901
LTSVLSPRLT RRGSKKRPAR SSHQELRREE GNQDQTGSLT QTRSSSKHVR
950 951
HASVPATFTP IVVPEPAMSV GPPVAAPEPV GFPVRGHPAL QAPSLEDVTK
1000 1001
RYMLTLHSGD VPAPGPVDLP CLPPSAPPST ETKPSGAARA TPDEPAPASK
1050 1051
CCSKPQVDMR KHVTMTLLDT EQSYVESLRT LMQGYMQPLK QPENSLLCDP
1100 1101
SLVDEIFDQI PELLEHHEQF LEQVRHCVQT WHAQQKVGAL LVQSFSKDVL
1150 1151
VNIYSAYIDN FLNAKDAVRV AKEARPAFLK FLEQSMRENK EKQALSDLMI
1200 1201
KPVQRIPRYE LLVKDLLKHT PEDHPDHPLL LDAQRNIKQV AERINKGVRS
1250 1251
AEEAERHARV LQEIEAHIEG MEDLQAPLRR FLRQEMVIEV KAIGGKKDRS
1300 1301
LFLFTDLIVC TTLKRKSGSL RRSSMSLYTA ASVIDTASKY KMLWKLPLED
1350 1351
TDIIKGASQA TNRETIQKAI SRLDEDLATL GQMSKLSESL GFPHQSLDDA
1400 1401
LRDLSAAMHR DLSEKQALCC SLAFPPTKLE LCATRPEGTD SYIFEFPHPD
1450 1451
ARLGFEQAFD EAKRKLASSK SCLDPEFLKA IPIMKTRSGM QFSCAAPTFS
1500 1501
SCPEPAPEVW VCNSDGYVGQ VCLLSLRAEP DVEACIAVCS ARILCIGAVP
1550 1551
GLQPRCPREQ PEPLRNPPET TLESTGPELD VEATAEEEAA TTLAEPGPQP
1600 1601
CLHISISGSG LEMEPGPAKG DPQPELVPFD SDSDDESSPS PSGTLQSQAS
1650 1651
QSTISSSFGN EETPSSKEAT AETTSSEEEQ EPGFLSLSGS FGPGGPCGTS
1700 1701
PMDGRALRRS SRGSFTRGSL EDLLSVDPEA YQSSVWLGTE DGCVHVYQSS
1750 1751
DSIRDRRNSM KLQHAASVTC ILYLNNKVFV SLANGELVVY QREAGRFWDP
1800 1801
QNFKSMTLGS QGSPITKMVS VGGRLWCGCQ NRVLVLSPDT LQLEHTFYVG
1850 1851
QDSSRSVACM VDSSLGVWVT LKGSAHVCLY HPDTFEQLAE VDVTPPVHRM
1900 1901
LAGSDAIIRQ HKAACLRITA LLVCAELLWV GTSAGVVLTI PTSPSTVSCP
1950 1951
RAPLSPAGLC QGHTGHVRFL AAVQLPEGFN LLCSTPPPPP DTGPEKLPSL
2000 2001
DHRDSPRRRG PTSARPKMLV ISGGDGSEDF RLSSGGGGSS ETVGRDDSTN
2050 2051
HLLLWRV
2057
Show the unformatted sequence. |
| Checksums: |
CRC64:CCB48100B1ECE03C
MD5:9a773f20ebeb14145f5ea3756a8fbe51
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
