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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PNKP_HUMAN (Q96T60)

Summary

This is the summary of UniProt entry PNKP_HUMAN (Q96T60).

Description: Bifunctional polynucleotide phosphatase/kinase Polynucleotide 3'-phosphatase Polynucleotide 5'-hydroxyl-kinase EC=3.1.3.32 EC=2.7.1.78
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 521 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 4 31
disorder n/a 33 84
disorder n/a 105 142
Pfam A PNK3P 166 328
low_complexity n/a 229 242
Pfam A AAA_33 367 489

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96T60. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGEVEAPGRL WLESPPGGAP PIFLPSDGQA LVLGRGPLTQ VTDRKCSRTQ
50
51
VELVADPETR TVAVKQLGVN PSTTGTQELK PGLEGSLGVG DTLYLVNGLH
100
101
PLTLRWEETR TPESQPDTPP GTPLVSQDEK RDAELPKKRM RKSNPGWENL
150
151
EKLLVFTAAG VKPQGKVAGF DLDGTLITTR SGKVFPTGPS DWRILYPEIP
200
201
RKLRELEAEG YKLVIFTNQM SIGRGKLPAE EFKAKVEAVV EKLGVPFQVL
250
251
VATHAGLYRK PVTGMWDHLQ EQANDGTPIS IGDSIFVGDA AGRPANWAPG
300
301
RKKKDFSCAD RLFALNLGLP FATPEEFFLK WPAAGFELPA FDPRTVSRSG
350
351
PLCLPESRAL LSASPEVVVA VGFPGAGKST FLKKHLVSAG YVHVNRDTLG
400
401
SWQRCVTTCE TALKQGKRVA IDNTNPDAAS RARYVQCARA AGVPCRCFLF
450
451
TATLEQARHN NRFREMTDSS HIPVSDMVMY GYRKQFEAPT LAEGFSAILE
500
501
IPFRLWVEPR LGRLYCQFSE G                               
521
 

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Checksums:
CRC64:22B5C94D41E62516
MD5:63ccfe607e269a5d2aeb4ce20ba3a12e

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.