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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NHEJ1_HUMAN (Q9H9Q4)

Summary

This is the summary of UniProt entry NHEJ1_HUMAN (Q9H9Q4).

Description: Non-homologous end-joining factor 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 299 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A XLF 11 173
disorder n/a 227 252
disorder n/a 254 255
disorder n/a 257 295
disorder n/a 297 299

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9H9Q4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEELEQGLLM QPWAWLQLAE NSLLAKVFIT KQGYALLVSD LQQVWHEQVD
50
51
TSVVSQRAKE LNKRLTAPPA AFLCHLDNLL RPLLKDAAHP SEATFSCDCV
100
101
ADALILRVRS ELSGLPFYWN FHCMLASPSL VSQHLIRPLM GMSLALQCQV
150
151
RELATLLHMK DLEIQDYQES GATLIRDRLK TEPFEENSFL EQFMIEKLPE
200
201
ACSIGDGKPF VMNLQDLYMA VTTQEVQVGQ KHQGAGDPHT SNSASLQGID
250
251
SQCVNQPEQL VSSAPTLSAP EKESTGTSGP LQRPQLSKVK RKKPRGLFS 
299
 

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Checksums:
CRC64:BC5C68076A5E7A96
MD5:2689d36cad75073f25589afc62062a7f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
XLF 11 - 169 2QM4 B 11 - 169 Jmol AstexViewer SPICE
11 - 173 2QM4 A 11 - 173 Jmol AstexViewer SPICE
C 11 - 173 Jmol AstexViewer SPICE
D 11 - 173 Jmol AstexViewer SPICE
2R9A A 11 - 173 Jmol AstexViewer SPICE
B 11 - 173 Jmol AstexViewer SPICE
3Q4F A 11 - 173 Jmol AstexViewer SPICE
B 11 - 173 Jmol AstexViewer SPICE
E 11 - 173 Jmol AstexViewer SPICE
F 11 - 173 Jmol AstexViewer SPICE
3RWR D 11 - 173 Jmol AstexViewer SPICE
E 511 - 673 Jmol AstexViewer SPICE
H 11 - 173 Jmol AstexViewer SPICE
I 511 - 673 Jmol AstexViewer SPICE
L 11 - 173 Jmol AstexViewer SPICE
M 511 - 673 Jmol AstexViewer SPICE
O 11 - 173 Jmol AstexViewer SPICE
Q 511 - 673 Jmol AstexViewer SPICE
S 11 - 173 Jmol AstexViewer SPICE
T 11 - 173 Jmol AstexViewer SPICE
W 511 - 673 Jmol AstexViewer SPICE
X 511 - 673 Jmol AstexViewer SPICE
3SR2 C 11 - 173 Jmol AstexViewer SPICE
D 11 - 173 Jmol AstexViewer SPICE
G 11 - 173 Jmol AstexViewer SPICE
H 11 - 173 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.